Question
Flux balance analysis assumes that all metabolites inside a cell satisfy this condition. For 10 points each:
[10m] Name this condition that occurs in a chemical reaction network if every accumulation term equals zero. Three distinct examples of this condition can satisfy mass and energy balances inside a CSTR.
ANSWER: steady-state concentrations [or stationary states; accept pseudo-steady states or quasi-steady-state; or SS or PSS or QSS; prompt on descriptive answers like not changing or fixed or static over time; prompt on positive equilibria or equilibrium or pseudoequilibrium]
[10e] Steady-state concentrations are eigenvectors of a matrix that encodes rates along with these values for every reaction in the network. Molarity is exponentiated by these coefficients in the law of mass action.
ANSWER: stoichiometric coefficients [or stoichiometry]
[10h] The trajectory to steady-state for discrete molecules in a network can be computed using this stochastic simulation algorithm, which samples chemical reactions from the distribution of their rates in the master equation.
ANSWER: Gillespie algorithm [or Doob–Gillespie algorithm]
Data
| Team | Opponent | Part 1 | Part 2 | Part 3 | Total |
|---|---|---|---|---|---|
| Chicago A | Harvard A | 0 | 0 | 10 | 10 |
| Claremont A | NYU A | 0 | 0 | 0 | 0 |
| Columbia A | WUSTL B | 0 | 10 | 0 | 10 |
| Cornell A | Johns Hopkins A | 10 | 10 | 0 | 20 |
| Florida A | Columbia B | 0 | 10 | 0 | 10 |
| Florida B | Chicago C | 0 | 0 | 0 | 0 |
| Indiana A | Purdue A | 0 | 0 | 0 | 0 |
| Iowa State A | Virginia A | 0 | 0 | 0 | 0 |
| MIT A | Duke A | 10 | 0 | 0 | 10 |
| Michigan A | Penn State A | 0 | 0 | 0 | 0 |
| Minnesota A | Maryland A | 0 | 10 | 0 | 10 |
| North Carolina A | Imperial A | 10 | 10 | 10 | 30 |
| Northwestern A | Minnesota B | 10 | 0 | 0 | 10 |
| Ohio State A | McGill A | 0 | 10 | 0 | 10 |
| Penn A | Vanderbilt A | 10 | 10 | 0 | 20 |
| Rutgers A | Houston A | 0 | 10 | 0 | 10 |
| Stanford A | Brown A | 10 | 10 | 0 | 20 |
| UC Berkeley A | Chicago B | 0 | 0 | 0 | 0 |
| UC Berkeley B | Rutgers B | 10 | 0 | 0 | 10 |
| WUSTL A | Toronto A | 0 | 0 | 0 | 0 |
| Yale A | Texas A | 0 | 10 | 10 | 20 |
| Yale B | South Carolina A | 0 | 10 | 0 | 10 |